Division of Neuroscience
Yerkes National Primate Research Center
One of our major goals is to identify the evolutionary specializations of the human brain, which we do by comparing humans to chimpanzees and to other nonhuman primates. We want to understand the extent to which evolutionary expansion of the human brain was accompanied by the addition of new areas or by the enlargement and internal reorganization of existing areas. To this end, we carry out comparative studies of cortical organization using immunocytochemistry and other techiniques that are useful for mapping cortical areas and investigating the laminar and cellular organization of cortex. Recently, we have begun to employ genomics techniques to identify genes that are differentially expressed in human brains, followed by in situ hybridization and immunocytochemical studies to demonstrate where the genes identified by genomics are expressed in the nervous system.
View publications on PubMed